scientist岗位职责

Job Description
PPD, a world leading laboratory clinical research company, will be opening a state-of-the art laboratory in Suzhou New District in March 2020. PPD Laboratories offer the most comprehensive set of laboratory services available in the industry. Our services are designed to accelerate pharmaceutical development fsmall molecules, biologics vaccines, allowing our clients to make faster decisions about their compounds, fall phases of pharmaceutical development.
As a Assist/Associate in the Vaccine Sciences department, you will use state-of-the-art technologies techniques to perform high-quality sample analysis testing fkey pharmaceutical biotech clients across the industry. Your role serves as an integral piece in helping PPD accomplish our goal of helping bring life-changing therapies to market.
Learn more about Vaccine Sciences at http://www.ppdi.com/Services/Laboratories/Vaccines-and-Biologics-Labs
At PPD we hire the best, develop ourselves each other, recognize the power of being one team. Its not just talk - our award-winning training programs speak fthemselves!
Responsibilities fthe assist/associate scientist may include:
• Performs a variety of routine sample preparation analysis procedures to
quantitatively measure pharmaceutical biopharmaceutical compounds in a
variety of formulations and/biological matrices fstability analytical
testing.
• Trains on routine operation, maintenance theory of analytical
instrumentation, SOPs regulatory guidelines.
• Communicates project status to project leader.
• Maintains a laboratory notebook completes all laboratory documentation in
clear accurate language according to SOP GLPs.
• Performs daily work assignments accurately, in a timely safe manner.
• Reviews, interprets, analyzes data ftechnical, quality compliance to
protocols, methods, SOPs, client criteria Good Manufacturing Practices
(GMP) Good Laboratory Practices (GLP).
• Performs self peer review of the data faccuracy compliance with reporting requirements prito submission to QA issuance to customers.
The Assist/Associate Scientist is expected to follow validated experimental bioanalytical procedures, to perform PCR, functional antibody, neutralization antibody ,ELISA assays support pharmaceutical product development, testing evaluation in a GLP regulatory lab environment.
The Assist/Associate Scientist will work both independently in a team setting with occasional direct supervision from a group leader. In addition, the Assist/Associate Scientist is responsible fthe review compilation of results, use of reporting software review of SOPs.
职位要求：
Education Experience:
• B.S Master.Degree in lab sciences such as Biology, Chemistry, Biochemistry, Medicine ,Biotechnology, Immunology, Virology, Bacteriology, Clinical Lab Sciences related science field
• 2+ years working experience
Automation platform (Hamilton,Tecan,Bravo) experience
Knowledge, Skills Abilities:
• Support testing analysis in the vaccine sciences department (run assays, perform testing analysis, prepare samples, prepare, maintain review lab documentation)
• Manual dexterity (pipetting, operate lab equipment, perform lab techniques)
• Experience performing assays, bioassays, immunoassays, ELISA, PCR, antigen/antibody testing, functional assays similar testing, cell culture
• Training experience with microbiological lab techniques a plus (such as sample analysis, bacterial identification, gram staining, streaking, plating, isolation of colonies, bacterial cell culture, mammalian cell culture, cell line maintenance, passaging of cells, sample preparation, molecular techniques similar relative experience)
• Understanding of aseptic sterile technique (such as training experience with maintaining sterile field, clean bench space, BSL I, BSL II, Fume hood, flow hood, biosafety cabinet similar)
• Follow lab safety guidelines, use of lab safety PPE (gloves, goggles, lab coat etc) use appropriate aseptic techniques
• Communicate effectively follow detailed written verbal instruction
• Cooperate with coworkers within anganized team environment work alone with supervision
• Manage time effectively to complete assignments in expected time frame
• Maintain a laboratory notebook complete all documentation with clear accurate language according to the Standard Operating Procedures
Our offer: As a compensation, you will be provided with a competitive remuneration, corporate trainings the opportunity to become a part of a fast growing, multinational company. At PPD, we encourage our employees to demonstrate creativity, innovation fresh insights as well as a solution-focused approach. We also value teamwork, camaraderie enthusiasm. At PPD we hire the best, develop ourselves each other, recognize the power of being one team. Its not just talk - our award-winning training programs speak fthemselves! This is a full-time, permanent position based in Suzhou

SUMMARY OF THE ROLE
The Bioanalysis Translational Medicine department centers on data‑driven bioanalysis translational research, leveraging molecular/protein assays, cellular function phenotyping, biomarker with PK/PD platforms to support cell therapy programs including CAR‑T mRNA‑LNP/lentiviral in vivo CAR.
The role holder will be accountable fmethod establishment sample analysis fIIT-stage clinical samples by qPCR/ddPCR, including CAR VCN, RCL other biomarkers. This role requires experience in the CAR-T industry a background in PCR techniques to support analytical method development, transfer, validation, sample testing, data analysis; it also involves assisting the Bioanalysis Translational Medicine department with external project management. The role holder is accountable fensuring that all activities are delivered demonstrating behaviours values aligned to AstraZeneca Code of Conduct supporting policies, standards procedures, including compliant management of Budget, Safety, Health Environment.
ROLE & RESPONSIBILITIES
● Sample pre-processing traceability: Define execute standards fcollection, transport, storage, receipt of blood/plasma, bone marrow, tissue (fresh/FFPE), cellular samples; perform DNA/RNA extraction QC (Qubit, A260/280); establish standardized workflows to ensure end-to-end traceability compliance.
● Sample testing: Conduct qPCR/ddPCR assays per SOPs (VCN, persistence/clearance, target mRNA expression, RCL); maintain a comprehensive control system (positive/negative controls, NTC, spike in standards); design optimize primers/probes, short amplicon strategies, anti inhibition approaches as needed to ensure batch stability reliable results.
● Manage external alliance: Define technical plans quality requirements; evaluate CROs; Work effectively with procurement to contract the biomarker operations to deliver fit-fpurpose laboratory testing from receipt delivery of results, compliant with clinical sample testing guidelines.
● Data analysis delivery: Perform statistical analysis interpretation; integrate with flow cytometry, ELISA, PK/PD data; deliver standardized reports actionable translational conclusions.
● Complete protocols, reports, other documentation during the method establishment process; write experimental records accurately promptly, ensuring the correctness completeness of experimental data reports.
● Clinical project support: review clinical protocols relevant sections of ICFs, assist HGR application, data management, other processes by working closely with clinical team other supporting functions.
● Monitensure compliance with all AstraZeneca Policies Standards, local law/regulation, immediately address instances of non-compliance.
REQUIREMENTS
Essential:
● Master’s degree above in molecular biology, genomics, bioinformatics, immunology, a related field; at least 5 years of experience in molecular testing, translational medicine, clinical laboratory work.
● Having experience in developing, validating, testing PCR-based analytical methods fclinical samples, including independently establishing new methods.
● Knowledge of clinical testing procedures applicable laboratory testing regulations such Good Clinical Practice, Good Clinical Practice, CAP.
● Experience of working with testing partners to drive timely successful outcomes, through effectively working across internal external boundaries.
● Ability to identify risks escalate appropriately
Skills & Capabilities
● Good interpersonal skills ability to act as an ambassadfBioanalysis Translational Medicine internally externally
● Ability to interact successfully with multiple partners across functional boundaries
● Ability to work independently, designing, executing tasks
● A confident team player who is assertive but willing to listen learn from the views of others
● Excellentganizational skills, with the proven ability to deliver high quality work under pressure against tight timelines
Desirable:
● An understanding of drug companion diagnostic assay co-development commercialization experience working in early late phase projects
● Demonstrates a clear understanding of the scientific rationale underpinning PK/PD testing in cell therapy.
● Demonstrated experience in developing, optimizing, validating PCR-based assay.
● Possesses practical experience in NGS, IHC, ISH/FISH, demonstrates solid theoretical methodological knowledge in these areas.

SeniScientist - Formulation & Materials Science
Location: Shanghai, China
As a key member of our Formulation & Materials Science Shanghai team, you will leverage deep expertise in physical chemistry, colloidal science, formulation science to innovate develop liquid delivery systems ffragrance, flavor, nutrient other active ingredients, driving advancements in delivery technologies providing integrated solutions four clients. At dsm-firmenich, being a force fgood is not optional. Diversity, Equity & Inclusion is a shared responsibility woven our daily work, benefiting to our People, Customers & Communities driving business value. Equal access to opportunities is a given, belonging is a shared feeling, authenticity is celebrated.
Your Key Responsibilities
• Lead contribute global cross-functional innovation projects, collaborating closely with partners across Science & Research Business Units.
• Conceive, design execute research programs fassigned projects, be responsible fdocumentation, data analysis, result reporting.
• Develop novel delivery technologies formulation strategies with improved performance fhealth, beauty care applications products.
• Monitemerging scientific technological trends in encapsulation & delivery technology, integrate relevant findings in-house projects to strengthen outcomes intellectual property.
• Provide technical leadership to juniteam members; ensure that laboratory work is conducted with full compliance to Safety, Health, Environment regulations.
• Deliver scientific technical support at customer events collaborate with business partners to address resolve technical challenges.
We Bring
• Opportunities to further develop knowledge expertise, grow advance, allowing you to embrace innovation take initiative.
• Diversity of exciting projects related to health, beauty care, with access to state-of-the-art lab facilities collaboration with experts from around the globe.
• Opportunity to build a career making a significant impact on billions of lives, with the freedom to shape your own path.
• Responsibility accountability in living company values driving sustainable solutions.
• Recognition celebration of your efforts accomplishments.
• Supportive environment where individuals are empowered to progress contribute to meaningful change.
You Bring
• PhD in Colloidal Science, Physical Chemistry, Polymer Science, Food Science a related field (equivalent qualification) with extensive research experience in formulation delivery technologies, ideally with industry experience.
• Extensive knowledge expertise in soft matter physics, emulsion/colloid formulation, encapsulation/other delivery mechanisms.
• Solid laboratory experimental skills hands-on experience of a variety of analytical techniques (e.g. light scattering, rheology, tensiometry).
• Demonstrated ability to design experiments, interpret complex data, translate insights formulation strategies.
• Experience in consumer products, flavors/fragrances, nutraceuticals, beauty/personal care industries is a plus.
• Proficiency in spoken written English is mandatory.
About dsm-firmenich
At dsm-firmenich, we don’t just meet expectations – we go beyond them.
Join our global team powered by science, creativity, a shared purpose: to bring progress to life.
From elevating health to making fortified food sustainable skincare, the impact of your work here will be felt by millions – every single day. Whether it’s fragrance that helps you focus, alternative meat that’s better fthe planet, reducing sugar without losing flavor, this is where you help shape the future of nutrition, health, beauty feveryone, everywhere.
while you’re making a difference, we’ll make sure you’re growing too. With learning that never stops, a culture that lifts you up the freedom to move across businesses, teams, borders. Your voice matters here. your ideas? They’re essential to our future.
Because real progress only happens when we go beyond, together.
Inclusion belong equal opportunities
At dsm-firmenich, we believe being a force fgood starts with the way we treat each other. When people feel supported, included, free to be themselves, they do their best work – that’s exactly the kind of culture we’re building. A place where opportunity is truly equal, authenticity is celebrated, everyone has the chance to grow, contribute, feel they belong.
We’re proud to be an equal opportunity employer, we’re serious about making our hiring process as fair inclusive as possible. From inclusive language diverse interview panels to thoughtful sourcing, we’re committed to reflecting the world we serve.
We welcome candidates from all backgrounds — no matter your gender, ethnicity, sexualientation, anything else that makes you, you.
if you have a disability need any support through the application process, we’re here to help – just let us know what you need, we’ll do everything we can to make it work.
Agency statement
We’re managing this search directly at dsm-firmenich. If you’re applying as an individual, we’d love to hear from you. We’re not accepting agency submissions proposals involving fees commissions fthis role.