Nanchang Royo Biotech Co., Ltd. is a national high-tech enterprise established in June 2011 (among the first batch of high-tech enterprises in 2018), mainly focusing on the industrial application of HDST/PDX drug screening technology in tumor personalized treatment and new drug development. The company has established a relatively complete cell and animal experiment platform. Its SPF-grade animal room has obtained the Laboratory Animal Use License. At present, it has been granted 9 utility model patents, and 4 invention patents are under review. The founder is a founding member of the PDX Group of the Biobank Branch of the China Medicinal Biotech Association and is participating in the formulation of PDX industry standards. The company's development has received care and help from leaders at all levels. Then Vice Governors of Jiangxi Province Lei Zhongqiong and Xie Ru, former Secretary of the Jiangxi Provincial Committee of the Communist Youth League Zeng Ping and many other leaders visited our company for inspection and guidance.
The HDST/PDX drug screening platform integrates the respective advantages of the HDST (Hydrogel embedded histoculture drug sensitivity test) model and the PDX (Patient-derived tumor xenograft models) model with independent intellectual property rights, and plays an important role in personalized tumor treatment and new drug development: 1. Use HDST/PDX models to conduct personalized one-to-one pharmacodynamic testing for tumor patients, predict the effectiveness of various combination chemotherapy regimens or the latest drugs for tumor patients, avoid the risk of drug testing on the patients themselves, provide optimal personalized treatment plans for tumor patients and doctors, improve patients' quality of life, and thereby prolong patients' lives; 2. Use HDST/PDX models and related medical big data to support cancer research institutions and pharmaceutical companies in conducting clinically relevant translational research, evaluate the anti-cancer efficacy of candidate compounds in a large number of HDST/PDX models, reduce the risk and cost of anti-tumor drug development, and accelerate the drug development process.
Royo Biotech is a well-known company in the PDX field. It has completed the construction of more than 1,200 PDX models, and among the successfully constructed PDX models, 10 were established for the first time globally. The company's HDST/PDX drug screening technology has attracted extensive cooperation from many top-tier Class III Grade A hospitals in China (Tongji, Union, Xiangya, Zhongshan, Zhejiang University Children's Hospital, etc.) and pharmaceutical giants (Johnson & Johnson, Amgen, WuXi AppTec, etc.). The company has achieved good results in various national entrepreneurship competitions, such as: First Prize in the Precision Medicine Field of the 2018 "Maker China" Great Health Innovation and Entrepreneurship Competition, Third Prize in the "Enterprise Group" of the 2018 "Maker China" Jiangxi Innovation and Entrepreneurship Competition, and Third Prize in the "Enterprise Group" of the Nanchang Selection Competition of the Third "China Chuangyi" Innovation and Entrepreneurship Competition and the First Jiangxi-Nanchang "Chuangling Meihao" Entrepreneurship Competition.
The company is currently expanding nationwide and establishing tumor personalized precision drug screening centers in large and medium-sized cities across the country (Nanchang, Guangzhou, and Shanghai have been completed), to screen the optimal treatment plans for tumor patients. We welcome outstanding talents interested in the field of tumor precision treatment to join us and jointly achieve a brilliant career.
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