Wuhan Beidu Biotechnology Co., Ltd. was established in 2010. It is a high-tech enterprise wholly controlled by Guangdong Guanhao Biotechnology Co., Ltd. (Stock Code: 300238) in Wuhan, specializing in biological resource preservation, omics research, and technology development. In 2013, Beidu Biotechnology was approved by the Hubei Provincial Department of Science and Technology and the Wuhan National Bioindustry Base Construction Management Office to establish the Hubei Provincial Human Cell Bank and the Wuhan National Bioindustry Base Biological Sample Bank, obtaining qualifications for the preservation of cells and other biological samples, and jointly built the Wuhan University People's Hospital Cell Preservation Bank with Wuhan University People's Hospital. This bank is a public technology platform for biological sample preservation and biological resource development and services in Hubei Province. In 2015, it was approved by the Hubei Provincial Department of Science and Technology to obtain administrative permission for biological sample collection, and has qualifications for biological sample collection and preservation. In December 2015, the Hubei Provincial Development and Reform Commission, in order to promote the industrialization of the company's project using stem cells to produce artificial blood components, approved Guanhao Group to establish a cell resource development and operation platform in Central China in Wuhan, creating a foundation for the industrialization of the project. The project plans a total investment of 350 million yuan. The company has signed agreements with more than a dozen hospitals and research institutions, including Zhongnan Hospital of Wuhan University, Wuhan University People's Hospital, and Hubei Maternal and Child Health Hospital, to jointly build the Hubei Provincial Human Cell Bank, carrying out disease biological sample collection, collection, preservation, construction of bioinformatics databases, and industrialization development of biological resources. Currently, it is establishing a disease placental biological sample bank, cell resource bank, birth defect biological sample bank, and biological sample banks for major diseases such as tumors and cardiovascular diseases. The company has a GMP workshop for cells and tissue engineering products, a biological sample bank, and laboratories covering 3,800 square meters. It has passed quality verification by the Hubei Provincial Institute for Food and Drug Control and national ISO-9001 quality certification. It has the capacity to preserve 1 million copies of cells and other biological samples. The company has applied for 5 patents, including tissue-engineered skin for the treatment of vitiligo and production of artificial blood components from placental blood hematopoietic stem cells. Among them, the umbilical cord mesenchymal stem cell culture technology (Patent No. ZL201110110104.3) and anti-highly pathogenic avian influenza H5N1 Class I chemical drug have been granted patent authorization (Patent No. ZL:20121057.9), and 4 medical device registration certificates have been obtained.
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