Liuhe Ningyuan

Beijing Liuhe Ningyuan Pharmaceutical Technology Co., Ltd., founded in 2010, is a professional CRO/CDMO service provider co-founded by graduates of Tsinghua University, focusing on the field of chemical synthesis of small molecule innovative drugs. The company has established its own brand, Bellen, and built a one-stop service platform for the chemical synthesis of small molecule innovative drug research and development, providing global pharmaceutical companies and innovative drug companies with one-stop chemical synthesis services covering all stages of small molecule new drug R&D. Bellen, with its excellent R&D team and high-quality R&D services, has become a rising star in the industry, with customers widely distributed in major international markets such as Europe, the United States, and Japan. Bellen's headquarters and early-stage R&D center (Beijing Liuhe Ningyuan Pharmaceutical Technology Co., Ltd.) is located in Beijing, with a process R&D center in Shanghai (Shanghai Handao Pharmaceutical Technology Co., Ltd.), a pilot scale-up and production base in Shandong (Yantai Ningyuan Pharmaceutical Co., Ltd.), and market development centers in the United States, France, Japan, and other countries. Bellen has nearly a thousand employees, including overseas scientists, former executives of international pharmaceutical companies, and high-quality talents such as PhDs from Tsinghua University, the Chinese Academy of Sciences, and other higher education institutions. Bellen's headquarters and early-stage R&D center, Beijing Liuhe Ningyuan Pharmaceutical Technology Co., Ltd., was established in 2010 and is located in the Liandong U Valley Industrial Park, Renhe Town, Shunyi District. It is a national high-tech enterprise and a Zhongguancun high-tech enterprise. The company has R&D laboratories of over 10,000 square meters that meet international standards, equipped with various internationally advanced testing equipment including Bruker NMR, Agilent LC-MS, Agilent GC-MS, Agilent HPLC, Agilent UPLC, and preparative HPLC. The company has more than 200 R&D personnel and can provide R&D services from milligram, gram to kilogram scales. Shanghai Handao Pharmaceutical Technology Co., Ltd., established in 2017, is located in the Qiyate Industrial Park, Minhang District, Shanghai. It has modern laboratories covering an area of over 2,500 square meters, more than 120 R&D personnel, and is equipped with various professional analytical instruments such as NMR spectrometers, liquid chromatography-mass spectrometry, inductively coupled plasma optical emission spectrometers, liquid chromatographs, GC (Agilent), and automatic reaction calorimeters. The company serves as Bellen's process R&D center, responsible for production process research and development, screening and optimization of new synthetic routes, and early-stage process R&D, providing technical support for Bellen's pilot production in Yantai. Yantai Ningyuan Pharmaceutical Co., Ltd., established in 2014, is located in the high-tech industrial agglomeration area of Zhaoyuan City, Yantai, Shandong. It covers an area of nearly 100 mu, has five multi-functional production workshops, and has built first-class R&D laboratories, pilot platforms, and high-performance synthesis and analysis laboratories. Adopting internationally aligned equipment, processes, and management models, and relying on the strong R&D strength of Beijing and Shanghai, it has become an excellent pilot scale-up and production base in the field of new drug R&D chemical synthesis, leading the creation of a modern pharmaceutical industrial park with Zhaoyuan characteristics.